Sukanta Das

Designation:
Visiting Instructor
Department:
Pharmacology and Regenerative Medicine
University:
University of Illinois at Chicago
Country:
USA
Email:
suri.sukanta@gmail.com
Journal Associated: Archives of Clinical Gastroenterology Biography:

I did my P.hD. in Biomedical Sciences from Institute of Liver and Biliary Sciences (ILBS, New Delhi, India). After finishing P.hD. I joined the College of Medicine, University of Illinois at Chicago and worked as postdoctoral research associate in the department of Pathology (from 8/15/2018 to 5/19/2023) and Department of Pharmacology and Regenerative Medicine (from 9/20/2023 to 8/15/2023). Currently, working as a faculty member at the rank of Visiting Instructor in the Department of Pharmacology and Regenerative Medicine, College of Medicine, University of Illinois at Chicago.

My P.hD. and Postdoctoral training helps me to develop an in-depth knowledge about the underlying molecular and cellular mechanisms which play a pro-vital role in the inter-organ and cellular communication in physiological and pathological conditions. My research expertise includes good knowledge in the concept of pre-clinical and clinical biomedical studies; mice models related to biomedical sciences; working with human samples; good understanding and use of new cutting age high-through put technologies. My scholarly publications include articles in peer-reviewed journals such as Hepatology, Clinical Gastroenterology and Hepatology, Cellular and Molecular Gastroenterology and Hepatology, Hepatology Communication, Gastroenterology, Journal of hepatology, Scientific report, and others. My participation in professional conferences includes poster and oral presentations at national and international conferences such as The Liver Meeting (American Association for the Study of Liver Diseases, AASLD), International Liver Congress (European association for the Study of the Liver, EASL), Indian Society of Gastroenterology (ISG),

International Society for Hepatic Sinusoidal Research (ISHSR), ILBS-TATA invited talk at institute of Liver and Biliary Sciences. In the past as well as in present I am serving as reviewers in peer-reviewed journals such as Journal of Exploration of Digestive Diseases, Inflammation and in professional conferences such as the Liver Meeting and Digestive Disease Week organized by American Association for the Study of Liver Diseases (AASLD). Currently, I am also serving as editorial board member in Biomedical Sciences and review editor in Frontiers in Gastroenterology.

Publications List:

  1. Xiaodong Ge, Romain Desert, Fernando Magdaleno, Hui Han, Zhuolun Song, Sukanta Das, Dipti Athavale, Wei Chen, Ines Barahona, Daniel Lantvit, Hui Chen, Sunil Hwang, Natalia Nieto, “Redox-Sensitive High-Mobility Group Box-1 Isoforms Contribute To Liver Fibrosis Progression And Resolution In Mice”, Journal of Hepatology, 2023, DOI: 10.1016/j.jhep.2023.11.005.
  2. Dipti Athavale, Ines Barahona, Zhuolun Song, Romain Desert, Wei Chen, Hui Han, Sukanta Das, Xiaodong Ge, Sai Santosh Babu Komakula, Cindy Gao, Daniel Lantvit, Grace Guzman, Gaskell, Natalia Nieto, “Overexpression of hmgb1 in hepatocytes accelerates pten inactivation induced liver cancer”, Hepatology Communication, 2023, DOI: 10.1097/HC9.0000000000000311.
  3. Hui Han, Xiaodong Ge, Sai Santosh Babu Komakula, Romain Desert, Sukanta Das, Zhuolun Song, Wei Chen, Dipti Athavale, Harriet Gaskell, Daniel Lantvit, Grace Guzman, Natalia Nieto, “Macrophage-derived osteopontin (spp1) protects from non-alcoholic steatohepatitis”, Gastroenterology, 2023, DOI: 10.1053/j.gastro.2023.03.228.
  4. Wei Chen, Yameng Sun, Shuyan Chen, Xiaodong Ge, Wen Zhang, Ning Zhang, Xiaoning Wu, Zhuolun Song, Hui Han, Romain Desert, Xuzhen Yan, Aiting Yang, Sukanta Das, Dipti Athavale, Natalia Nieto, Hong You, “Matrisome gene-based subclassification of patients with liver fibrosis identifies clinical and molecular heterogeneities”, Hepatology, 2023, DOI: 10.1097/HEP.0000000000000423.
  5. Romain Desert 1, Wei Chen, Xiaodong Ge, Roselyne Viel, Hui Han, Dipti Athavale, Sukanta Das, Zhuolun Song, Daniel Lantvi1, Luis Cano3, Alexandra Naba, Orlando Musso, Natalia Nieto, “Hepatocellular carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular atrix remodeling and wnt/tgfb signatures, associated with poor outcome,” Hepatology, 2023, DOI: 10.1097/HEP.0000000000000362.
  6. Zhuolun Song, Hui Han, Xiaodong Ge, Sukanta Das, Romain Desert, Dipti Athavale, Wei Chen, Sai Santosh Babu Komakula, Daniel Lantvit and Natalia Nieto, “Deficiency of neutrophil high-mobility group box protein-1 in liver transplant recipients exacerbates early allograft injury in mice,” Hepatology, 2023, DOI: 10.1097/HEP.0000000000000346.
  7. Sukanta Das, Zhuolun Song, Hui Han, Xiaodong Ge, Romain Desert, Dipti Athavale, Sai Santosh Babu Komakula, Fernando Magdaleno, Wei Chen, Daniel Lantvit, Grace Guzman, Natalia Nieto, “Intestinal osteopontin protects from alcohol-induced liver injury by preserving the gut microbiome and the intestinal barrier function”, Cellular and Molecular Gastroenterology and Hepatology, 2022, https://doi.org/10.1016/j.jcmgh.2022.06.012.
  8. Dipti Athavale, Zhuolun Song, Romain Desert, Hui Han, Sukanta Das, Xiaodong Ge, Sai Santosh Babu Komakula, Wei Chen, Shenglan Gao, Daniel Lantvit, Grace Guzman, Natalia Nieto, “Ablation of high-mobility group box-1 in the liver reduces hepatocellular carcinoma but causes hyperbilirubinemia in Hippo signaling-deficient mice”, Hepatology Communication, 2022, https://doi.org/10.1002/hep4.1943.
  9. Romain Desert, Xiaodong Ge, Zhuolun Song, Hui Han, Daniel Lantvit, Wei Chen, Sukanta Das, Dipti Athavale, Ioana Abraham-Enachescu, Chuck Blajszczak, Yu Chen, Orlando Musso, Grace Guzman, Yujin Hoshida, Natalia Nieto, “Role of Hepatocyte-Derived Osteopontin in Liver Carcinogenesis”, Hepatology Communication, 2022, https://doi.org/10.1002/hep4.1845.
  10. Sukanta Das, Xiaodong Ge, Hui Han, Romain Desert, Zhuolun Song, Dipti Athavale, Wei Chen, Harriet Gaskell, Daniel Lantvit, Grace Guzman, Natalia Nieto, “The Integrated “Multiomics” Landscape at Peak Injury and Resolution From Alcohol-Associated Liver Disease”, Hepatology Communication, 2022, https://doi.org/10.1002/hep4.1793.
  11. Zhuolun Song, Wei Chen, Dipti Athavale, Xiaodong Ge, Romain Desert, Sukanta Das, Hui Han, Natalia Nieto, “Osteopontin takes center stage in chronic liver disease”, Hepatology, 2021, DOI: 10.1002/hep.31582 (Review article).
  12. Wei Chen, Romain Desert, Xiaodong Ge, Hui Han, Zhuolun Song, Sukanta Das, Dipti Athavale, Hong You, Natalia Nieto, “The Matrisome Genes From Hepatitis B–Related Hepatocellular Carcinoma Unveiled”, Hepatology Communications, 2021, https://doi.org/10.1002/hep4.1741.
  13. Hui Han, Romain Desert, Sukanta Das, Zhuolun Song1, Dipti Athavale1, Xiaodong Ge1, NataliaNieto, “Danger signals in liver injury and restoration of homeostasis”, Journal of Hepatology , 2020, DOI: 10.1016/j.jhep.2020.04.033 (Review article).
  14. Adil Bhat, Sukanta Das, Gaurav Yadav, Sudrishti Chaudhary, Ashish Vyas, Islam M, Abhishak C Gupta, Meenu Bajpai, Rakhi Maiwall, Jaswinder Singh Maras, Shiv K Sarin, “Hyperoxidized albumin modulates platelet and promotes inflammation through CD36 receptor in severe alcoholic  epatitis”, Hepatology Communication, 2020, DOI: 10.1002/hep4.1440.
  15. Harriet Gaskell, Xiaodong Ge, Romain Desert, Sukanta Das, Hui Han, Daniel Lantvit, Grace Guzman, Natalia Nieto, “Ablation of Hmgb1 in Intestinal Epithelial Cells Causes Intestinal Lipid Accumulation and Reduces NASH in Mice”, Hepatology Communication, 2020, DOI: 10.1002/hep4.1448.
  16. Jaswinder Singh Maras, Sukanta Das, Adil bhat, Ashish Kumar Vyas, Gaurav Yadav, Sudrishti Chaudhary, Sukriti Sukriti, Abhishak C gupta , Chagan Bihari, Rakhi Mahiwal, Shiv Kumar Sarin, “Dysregulated lipid transport proteins correlates with the pathogenesis and outcome in Severe Alcoholic Hepatitis”, Hepatology Communication, 2019, DOI: 10.1002/hep4.1438.
  17. Sukanta Das, Md. Shabir Hussain, Jaswinder Singh Maras, Jitendra Kumar, Shasthry S M, Suman Nayak, Vinod Arora, Rajan V, Shvetank Sharma, Rakhi Maiwall, Shiv Kumar Sarin, “Modification patterns of urinary albumin correlates with serum albumin and outcome in severe alcoholic  epatitis”, Journal of Clinical Gastroenterology, 2019, DOI: 10.1097/MCG.0000000000000990.
  18. Sukriti S, Choudhary MC, Maras JS, Sharma S, Thangariyal S, Singh A, Das S, Islam M, Sharma S, Trehanpati N, Gupta E, Sarin SK, “Extracellular vesicles from hepatitis B patients serve as reservoir of hepatitis B virus DNA”, Journal of Viral Hepatitis, 2018, DOI: 10.1111/jvh.12995.
  19. Jaswinder Singh Maras, Sukanta Das, Sachin Sharma, Sukriti Sukriti, Jitendra kumar, Ashish Kumar Vyas, Dhananjay Kumar, Adil Bhat, GauravYadav, Manish Chandra Choudhary, Shvetank Sharma, Guresh kumar, Chhagan Bihari, Nirupma Trehanpati, Rakhi Maiwall & Shiv Kumar Sarin, “Iron- Overload triggers ADAM-17 mediated infammation in Severe Alcoholic Hepatitis”, Scientific Reports, 2018, DOI: 10.1038/s41598-018-28483-x.
  20. Jaswinder Singh Maras, Sukanta Das, Shvetank Sharma, Saggere M Shasthry, Benoit Colsch, Christophe Junot, Richard Moreau, Shiv Kumar Sarin, “Baseline urine metabolic phenotype in  atients with severe alcoholic hepatitis and its association with outcome”, Hepatology Communication, 2018, DOI: 10.1002/hep4.1176.
  21. Sukriti S, Maras JS, Bihari C, Das S, Vyas AK, Sharma S, Hussain S, Shasthry S, Choudhary A, Premkumar M, Kumar D, Kumar G, Mukhopadhyay C, Kumar A, Trehanpati N, Rautou PE, Moreau R6, Sarin SK, “Microvesicles in hepatic and peripheral vein can predict nonresponse to corticosteroid therapy in severe alcoholic hepatitis”, Alimentary Pharmacology & Therapeutics, 2018, DOI: 10.1111/apt.14564.
  22. Sukanta Das, Jaswinder Singh Maras, Rakhi Maiwall, Shasthry S M, Md. Shabir Hussain, Shvetank Sharma, S. Sukriti, T.P.Singh, Shiv Kumar Sarin, “Molecular Ellipticity of Circulating Albumin- Bilirubin Complex Associates With Mortality in Patients With Severe Alcoholic Hepatitis”, Clinical Gastroenterology and Hepatology, 2018, DOI: 10.1016/j.cgh.2017.11.022.
  23. Shvetank Sharma, Jaswinder S. Maras, Sukanta Das, Shabir Hussain, Ashwani K. Mishra, Saggere M. Shasthry, Chhagan B. Sharma, Emmanuel Weiss, Laure Elkrief, Pierre-Emmanuel Rautou, Hélène Gilgenkrantz, Sophie Lotersztajn, Valérie Paradis, Pierre de la Grange, Christophe Junot, Richard Moreau, Shiv K. Sarin, “Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness”, Scientific Reports, 2017, DOI:  0.1038/s41598-017-07161-4.
  24. Sukanta Das, Jaswinder Singh Maras, Md Hussain, Shvetank Sharma, Paul David, Sukriti Sukriti, Saggere Muralikrishna Shasthry, Rakhi Maiwall, Nirupama Trehanpati, Tej P Singh, Shiv Kumar Sarin, “Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in  evere alcoholic hepatitis”, Hepatology, 2017, DOI: 10.1002/hep.28897.
  25. Jaswinder Singh Maras, Rakhi Maiwall, HC Harsha, Sukanta Das, Md Hussain, Chandan Kumar, Chhagan Bihari, Archana Rastogi, Manoj Kumar, Nirupama Trehanpati, Shvetank Sharma, Akhilesh Pandey, Shiv Kumar Sarin, “Dysregulated iron homeostasis is strongly associated with multiorgan failure and early mortality in acute-on-chronic liver failure”, Hepatology, 2015, DOI: 10.1002/ hep.27636.

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