Research Interest: My Research has
Focused on Understanding the BBB, Changes that Occur in the Blood-Tumor-Barrier
(BTB), and Drug Uptake Therein. To this End, I Have Worked and Gained
Significant Amount of Knowledge on Factors Influencing Anticancer Delivery and
Activity in Brain aBrain Metastases Developed from Breast Cancer in Mouse
Models. These Include: (1) How BBB is Altered in Mouse Models of Brain
Metastases of Breast Cancer. (2) Pharmacokinetic-Pharmacodynamic Relationship of
Anticancer Drugs in Brain Metastases. (3) in Vitro- In Vivo Correlations (IVIVC)
to Predict Optimum Therapeutic Concentrations for Treatment of Brain
Metastases. (4) Improving Targeted Anticancer Drug Delivery to Brain Tumors by
Inhibiting Efflux Transporters and Piggy Backing Drugs to Substrates of Influx
Transporters at the BBB.
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."