Research Interest: Human Saliva is a Fluid with Many Biological
Functions, and Essential for the Maintenance of Oral Health. It is known that
many Substances found in Peripheral Blood are also found in Saliva, although
generally lower concentrations are found in Saliva than in Blood. With the
emergence of New and Highly Sensitive Technologies, it is now possible to
analyse Minute Quantities of Substances in Human Saliva. Proteomics Technologies
have allowed the Determination of over 1,000 Proteins in Human Whole Saliva. Several
Studies Report Local and Systemic Biomarkers Appearing in Saliva, Including
Electrolytes, Blood Products, Enzymes and Tissue Destruction Molecules,
Inflammatory Markers as Well as Proteins Putatively Associated With Deadly
Diseases. Much of the Early Research on
Saliva Focused on its Local Biomarker Function, as an Indicator of Periodontal
Health. Support for the use of Saliva for the Detection of CVD and Myocardial
Infarction is Built on the Framework that many Serum Biomarkers Associated with
Inflammation, Atherosclerosis, Plaque Stability, and Myocardial Damage are
known and appear in Oral Fluids.
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