Juliano Andreoli Miyake

Designation:

Associate Professor

Department:

Morphological Science Department

University:

Federal University of Santa Catarina

Country:

Brazil

Email:

juliano.miyake@ufsc.br

Journal Associated: Annals of Cytology and Pathology Biography:

I have completed my PhD in Cell Biology, working with glioma cells and studying their behavior, using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and morphology, to study the angiogenesis response of endothelial cells in glioma, and the role of inflammatory mediators. After this, I did a post-doctoral period in Spain, where I worked with artificial skin and stem cells. I did other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer) worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I am an Associated Professor in Histology at Federal University of Santa Catarina- Brazil.

Research Interest: Cancer (Central nervous system and melanoma), angiogenesis, invasion and migration of tumoral cells

List of Publication:

1. Massaro,R; Brohem, C; Almeida, R; Rivelli, D; Miyake, J; Colquhoun, A; Barros, S; Engler, S. 4-nerolidylcatechol induces autophagy in human Glioblastoma cells.; Brazilian Journal of Pharmaceutical Sciences. Accepted for publication. 2017.
2. Miyake JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056.
3. Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11.
4. Garzón, JA. Miyake, M. González-Andrades, R. Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,. Wharton´s jelly stem cells. A novel cell source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013 Aug;2(8):625-32.
5. Benadiba M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51.
6. Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis. 2009 Mar 17;8:8.
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