Jing Yang

Designation:
Associate Researcher
Department:
Department of Medicine
University:
Hangzhou City University
Country:
China
Email:
yangjing@hzcu.edu.cn
Journal Associated: Annals of Alzheimer's and Dementia Care Biography:

I graduated with a Ph.D. in Human Anatomy and Histo-Embryology from Center for Neuroscience at Zhejiang University in 2016. Following my doctoral studies, I pursued postdoctoral research at the Center for Neurodegenerative Disease at Emory University in the United States from 2017 to 2018 and continued postdoctoral work at the College of Brain Science and Brain Medicine at Zhejiang University from 2018 to 2021. In April 2021, I joined the faculty at Hangzhou City University.

I am a dedicated neuroscientist with a strong academic background and extensive research experience in neurodegenerative and neurodevelopmental disorders. Since my master's degree, I have been engaged in research on neurodegenerative and neurodevelopmental disorders. As part of my master's studies, I participated in two National Natural Science Foundation (NSFC) projects concerning Alzheimer's disease (AD), systematically investigating the pathologic mechanisms of olfactory dysfunction in the early stages of Alzheimer's using mouse models. My Ph.D. research utilized autism mouse models to reveal the impact of the autism-related gene Shank3 on the development of cortical pyramidal neurons and discovered the role of the anterior cingulate cortex in social deficits. These findings were published in the prestigious journal Nature Neuroscience.

While at Emory University, my research continued to focus on AD, with a particular emphasis on the role of autophagy in the disease's pathological mechanisms. During my postdoctoral training at Zhejiang University, I led a project funded by the Youth Program of NSFC, investigating the role of calmodulin in neuronal development and participated in in a key project of NSFC investigating the coupling of neural activity to gene transcription in cognitive behavior, with findings published in the journals Neuron and Cell Reports. Additionally, I have been dedicated to studying the molecular control of biological age and frailty in midlife females.

As an associate researcher at Hangzhou City University, my research has primarily focused on the molecular mechanisms of brain aging, with a keen interest in the differences between males and females during the aging process and a commitment to the development of anti-aging drugs. My work has been supported by a Zhejiang Provincial Natural Science Foundation project.

My research has been recognized with the publication of 33 SCI papers as the first author or co-author in journals such as Neuron, Nature Neuroscience, and Cell Reports. These publications have received over 715 citations, reflecting the impact of my work on the scientific community. Additionally, I hold two authorized invention patents, showcasing my ability to translate scientific discoveries into practical applications.

My current position as an Associate Research Fellow at Hangzhou City University allows me to continue my research on the molecular mechanisms of aging and neurodegenerative diseases. I am passionate about contributing significantly to the field and improving human health through a better understanding of the brain. I am committed to mentorship and education, guiding the next generation of neuroscientists at Hangzhou City University.

In summary, my dedication to neuroscience, my commitment to mentorship, and my contributions to the scientific community have shaped my career as a researcher. I am inspired by the potential of my work to improve the lives of those affected by neurodegenerative conditions and to advance our collective understanding of the brain.

Research Interests: My research interests are interdisciplinary, combining cellular and molecular biology, neurophysiology, and translational medicine approaches to address significant questions in neuroscience. I am particularly focused on unravelling the mysteries of Alzheimer's disease and the molecular control of biological age and frailty, especially in midlife females. Meanwhile I am dedicated to explore the effects of chronic stress on brain aging which may provide valuable insights into the interplay between psychological stressors and physiological changes within the brain.

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